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ZYGOS favours the conception and formation of a healthy life thanks to the Preimplantation Genetic Diagnosis

The Preimplantation Genetic Diagnosisis a laboratory technique to detect genetic and chromosomal abnormalities in embryos obtained through in vitro fertilization, before being transferred to the uterus of the mother.
The PGD consists of performing genetic analysis of one or two cells of the embryo and thus, identify the healthy ones capable of being transferred to the uterus.

It is indicated in the following cases:

In couples or single women, at risk of transmitting chromosomal alterations or monogenic hereditary diseases.

In couples with a history of repeated abortions in the first trimester of pregnancy.

In implantation failure after several cycles of IVF-ICSI.

In severe seminal pathology.

In older women.

In couples with altered karyotype although they do not have abnormalities

In women who have had a child with malformations such as Down syndrome

For the identification of "histocompatibility" embryos with a sick brother. "The birth of this child would allow the use of "stem cells" of the umbilical cord blood, to be transplanted to his brother."

PGD for aneuploidy. Advanced age in women increases the risk of having a child with chromosomal abnormalities such as Down syndrome, Klinefelter syndrome, Edwards syndrome and others. By studying the main aneuploidy or the 23 pairs of chromosomes it is detected whether there is an alteration in the number of chromosomes in the embryo. PGD makes it possible to genetically test embryos and their selection increases the pregnancy rate of children without alterations.

PGD for translocations. Translocations in the karyotype may cause a chromosomal imbalance in embryos, leading to abortions or children with physical or psychological abnormalities.
When it comes to structural alterations (Robertsonian and reciprocal), it is possible to differentiate, in some cases, normal or balanced embryos from the unbalanced ones.

PGD for Monogenic Disease. There are more than 3,000 monogenic hereditary diseases that could be identified through PGD. It provides the ability to identify embryos with genetic alterations that cause these diseases, before being transferred to the uterus. There are a wide variety of monogenic diseases: Marfan syndrome, spinal muscular atrophy, Huntingtons Chorea C, H - Hemophilia A, fragile X syndrome, polycystic kidney disease, sickle cell anemia...